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doi: 10.1016/j.ejphar.2020.173551, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 417

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Nicotine not only directly acts on dopaminergic neurons, but also transiently enhances GABAergic neurons inhibitory drive on dopaminergic neurons by binding to nAChRs within GABAergic neurons in the VTA (Wooltorton et al., 2003